Alanine,N-[(9H-fluoren-9-ylmethoxy)carbonyl]-is a chemical reagent whose chemical name is Alanine,N-[(9H-fluoren-9-ylmethoxy)carbonyl]-. The following is a description of the nature, use, preparation and safety information of Alanine,N-[(9H-fluoren-9-ylmethoxy)carbonyl]:
Nature:
-Appearance: colorless crystal or crystalline powder
-Molecular formula: C22H19NO5
-Molecular weight: 373.39g/mol
-Melting point: 166-168 degrees Celsius
-Storage conditions: Store at room temperature, away from light and humidity
Use:
- Alanine,N-[(9H-fluoren-9-ylmethoxy)carbonyl]-is a commonly used amine group protection reagent, which is used to synthesize polypeptides and proteins in chemical synthesis. It protects the amino component and provides a protecting group that can be easily removed.
-It can be used in solid phase synthesis and liquid phase synthesis to synthesize biologically active polypeptides and other substances.
Preparation Method:
Alanine, the preparation of N-[(9H-fluoren-9-ylmethoxy)carbonyl]-is generally divided into the following steps:
1. Dissolve DL-alanine in an organic solvent, such as dimethylformamide (DMF).
2. Fmoc-Cl is added as a protecting group to carry out the reaction, and the reaction is carried out under alkaline conditions.
3. Next, it can be separated and purified by precipitation, filtration, washing and other steps.
Safety Information:
- Alanine,N-[(9H-fluoren-9-ylmethoxy)carbonyl]-is a chemical reagent and must comply with relevant laboratory safety operations.
-When using, avoid inhalation and skin contact, and wear appropriate personal protective equipment when necessary.
-It should be operated in a well-ventilated laboratory and avoid mixing with other substances.